Finally, further studies of T cell adoptive transfer and neutralization of cytokines, IFNγ and probably IL-17, are needed for determining the mechanisms underlying protection against ALA in baculovirus-immunized hamsters, as well as immunization studies using AcNPV-LC3 in an animal model closer to humans such as primates, in order to determine the safety and effectiveness of this system with view to its use as a strategy of vaccination against amoebiasis in humans. This evidence concerns the gene IFNG and amebiasis.