In this form on the tenth day of infection, the mammalian Tf-TfR complex normally found in early and recycled endosomes is associated with the PV [64]; furthermore, Tf was found to be delivered to PV and then endocytosed by intracellular amastigotes, so it could be possible that infection time enhances the endosomal delivery to the PV [63]. The gene discussed is TFRC; the disease is infection.