Parallel to findings of vWF, values of patients in the IWC-group were significantly higher compared to ICC-patients at 1 hour after CPB initiation (ICC: 3.2 ± 2.1 ng/mL; IWC: 5.2 ± 2.4 ng/mL; P = 0.011; Figure 5). The gene discussed is VWF; the disease is intrahepatic cholangiocarcinoma.