4 Edwards Edwards E E Yearwood Yearwood C C Sillibourne Sillibourne J J Baralle Baralle D D Eccles Eccles D D Identification of a de novo BRCA1 mutation in a woman with early onset bilateral Identification of a de novo BRCA1 mutation in a woman with early onset bilateral breast cancer Fam Cancer. This evidence concerns the gene BRCA1 and breast cancer.