SERPINE1 and type 2 diabetes mellitus: Simultaneously, we found that PAI-1 levels were significantly higher in T2D patients with ATIS compared to T2D patients without ATIS (7.75 ± 1.04 versus 4.57 ± 0.72 mU/L; P < 0.001) and in nondiabetics with ATIS compared to healthy subjects (4.78 ± 0.98 versus 3.49 ± 1.04 mU/L; P < 0.001) (Figure 3).