Statistically significant differences among ApN levels according to AER were found (F = 8.45, df = 2, P < 0.001) between type 1 diabetes (<30 = 12.37 ± 6.62, 30–300 = 21.38 ± 7.98, and >300 = 31.85 ± 18.05) and type 2 diabetes (<30 = 9.05 ± 5.63, 30–300 = 7.46 ± 4.58, and >300 = 5.26 ± 3.3) (Figure 1). The gene discussed is ANPEP; the disease is type 2 diabetes mellitus.