TLR4 and inflammatory bowel disease: Subgroup analysis based on ethnicity demonstrated that TLR4 polymorphism rs4986791C>T was associated with an increased risk of IBD risk in both Asian and Caucasian populations (Asians: allele model: OR = 1.608, 95% CI = 1.080~2.395, and P = 0.019; dominant model: OR = 1.517, 95% CI = 1.000~2.303, and P = 0.050; Caucasians: allele model: OR = 1.215, 95% CI = 1.042~1.415, and P = 0.013; dominant model: OR = 1.210, 95% CI = 1.030~1.421, and P = 0.020) (Figures 3(e) and 3(f)).