TLR4 and inflammatory bowel disease: Our findings demonstrated that TLR4 rs4986790A>G polymorphism significantly increased IBD risk (allele model: OR = 1.268, 95% CI = 1.124~1.431, and P < 0.001; dominant gene model: OR = 1.240, 95% CI = 1.090~1.409, and P = 0.001) (Figures 2(a) and 2(b) and Table 2).