Correlations between frequency of OGG1 mutations and menopausal age of breast cancer patients (Table 5) revealed that frequencies of three intronic mutations (g.9792260 ins_T; g.9793680G>A; and g.9798349T>A), two splice site mutations (g.9792109delT and g.9800972T>G), two 3′UTR mutations (9798848G>A and g.9798896T>C), and one missense mutation (Ser326Cys) were significantly higher (p < 0.05) in patients with earlier menopause (≤50 years) compared to controls and patients with late menopause (>50 years). The gene discussed is OGG1; the disease is breast cancer.