KISS1 and Infertility: Furthermore, we have recently demonstrated that exogenous kisspeptin-54 can stimulate egg maturation in women with infertility undergoing in vitro fertilization treatment (Jayasena et al., 2014), and Phase 2 studies are currently underway evaluating the effects of the kisspeptin analogue, TAK-448, on reproductive hormone secretion in healthy men (MacLean et al., 2014).