The present study assessed the effectiveness of the following seven fibrosis models, all of which comprise routine serum biomarkers and were found to have predictive value for significant liver fibrosis: age-platelet (PLT) index (API) (10), aspartate transaminase (AST) to alanine aminotransferase (ALT) ratio (AAR) (10,11), AST to PLT ratio index (APRI) (10,11), γ-glutamyl transpeptidase (GGT) to PLT ratio index (GPRI) (11), GGT-PLT-albumin (ALB) index (S index) (12), age-AST-PLT-ALT index (FIB-4) (13), and age-AST-PLT-ALT-international normalized ratio (INR) index (Fibro-Q) (14). Here, ALB is linked to Hepatic fibrosis.