SNCA and Parkinson disease: Differentially expressed probe sets with unadjusted p<0.05 between Braak alpha-synuclein stage 1–2 subjects and controls (4294 probe sets), resulted in 131 significantly altered probe sets between the transcriptome of the SN in Braak 1–2 and Braak 5–6 stages compared to controls, indicating that alterations of the same molecular mechanisms occur in iLBD and PD.