It has been suggested that angiogenesis in human NSCLC is mediated more by CXCR2 than CXCR1, possibly due to the fact that CXCR2 is a receptor for a more diverse array of ELR-CXC chemokines than CXCR1 [13–15]. The gene discussed is CXCR1; the disease is non-small cell lung carcinoma.