Furthermore, strong synergy (CI<0.5) was found in the wt p53-carrying parental A2780 cell line, which was established from an untreated cancer patient19 and outstanding synergy in the cisplatin-resistant A2780cis subline harboring wt p53 (Supplementary Figure S1c and d, respectively).20 The results from these studies are summarized in Table 1a. The gene discussed is TP53; the disease is cancer.