FCGR2B, present on several cell types including synovial mononuclear phagocytes, monocytes, neutrophils and myeloid dendritic cells (DCs) [164] is an inhibitory receptor with important regulatory functions on Fc receptor activation, which has been found overexpressed in RA synovium samples [165]. The gene discussed is FCGR2B; the disease is rheumatoid arthritis.