CAV1 and neoplasm: By evaluating the variability in the expression levels of MURC/CAVIN-4, CAV-3 and MHC, as detected in aRMS (n = 11) and eRMS (n = 7) tumors and skeletal muscle samples (n = 3) (Fig 1A), we found that the medians of CAV-3 and MHC in three groups were statistically different with a p-value of 0.0398 and 0.0222, respectively, while the levels of MURC/CAVIN-4 in tumor samples did not significantly differ from those observed in skeletal muscle (p-value = 0.1013) (Fig 1B).