We found that kidneys tissues of fetal kidney cells treated ARF rats have a lower mRNA expression of various pro-inflammatory cytokines including IL-1β, TNF-α and IFN-γ and protein expression of other potent inflammatory biomarkers including NFκB and ICAM-1 as well as higher mRNA expression of IL-10, which is a potent anti-inflammatory mediator. The gene discussed is IFNG; the disease is acute kidney injury.