Mice treated with oseltamivir prior to and during influenza infection had a reduced primary CD8+ T cell response to the epitopes DbNP366-374 and DbPA224-233 as well as the less prominent KbPB1703-711, DbPB1-F262-70 and KbNS2114-121, both at the site of infection and in the spleen. The gene discussed is CD8A; the disease is infection.