CD4 and infection: Interestingly, early after infection, at d7, there was an increase (p<0.05) in the total number of I-AbHA211 and I-AbNP311-specific CD4+ T cells in the MedLN of oseltamivir-treated mice as compared to controls, where at d10, virus-specific CD4+ T cell numbers were equivalent in the MedLN (Fig 6A and 6B).