INF2 mutations cause kidney disease in humans characterized by focal segmental glomerulosclerosis (FSGS) with or without Charcot–Marie–Tooth disease (Brown et al., 2010, Barua et al., 2013, Boyer et al., 2011, Gbadegesin et al., 2012). The gene discussed is INF2; the disease is focal segmental glomerulosclerosis.