To further elucidate the spectrum of DPR pathology in C9orf72 mutation patients, we analyzed the load of NCI, NII and DN pathology in 36 CNS regions using monoclonal antibodies for poly-GA (clone 5E9), poly-GR (clone 7H1) and poly-GP (clone 7A5) in five representative cases with comprehensive tissue collection, including two MND cases and three FTLD/MND cases (C9-1 to C9-5, see Table 1). The gene discussed is C9orf72; the disease is mild neurocognitive disorder.