REN and multiple endocrine neoplasia type 2B: The coexistence of PHEO and hyperreninemia secondary to renal artery stenosis has been previously reported [6], while only a paper, which described a 18 years follow-up in a family affected by MEN 2 B, found the association between adrenal medullary hyperplasia and renin-secreting juxtaglomerular tumor [7].