In consideration of this mechanism we tested our hypothesis via migration assay and found that docetaxel and GLIPR1-ΔΤΜ combination treatment resulted in significantly reduced numbers of migrated cells than docetaxel alone did, mimicking the result of docetaxel combined with CXCR4 inhibitor and supporting our hypothesis for a role for GLIPR1-ΔΤΜ suppression of PCa cell migration. This evidence concerns the gene CXCR4 and posterior cortical atrophy.