Moreover, knockdown of miR-337-3p resulted in no significant changes in the promoter activity and expression levels of MMP-14 in hepatocellular cancer HepG2 cells and prostate cancer PC-3 cells (Supplemenatry Figure S4A, Supplemenatry Figure S4B, Supplemenatry Figure S4C, and Supplemenatry Figure S4D). This evidence concerns the gene MMP14 and prostate carcinoma.