In addition, over-expression or knockdown of miR-337-3p in NB cells did not change the 3′-UTR luciferase activity of MMP-14 and VEGF (Supplemenatry Figure S3A and Supplemenatry Figure S3B), indicating no involvement of post-transcription regulation by miR-337-3p. This evidence concerns the gene MMP14 and neuroblastoma.