We then examined the influence of EGF on MMP9 transcription as well as on the transcription of additional MMPs (MMP-1, MMP-2, MMP-3, MMP-7, MMP-10, MMP-13, MMP14, MMP15) and of CD44, a cell adhesion glycoprotein implicated in EMT and cancer metastasis [42]. This evidence concerns the gene MMP13 and cancer.