APOE and atherosclerosis: However, aged Apoe−/−Ltbrfl/flTagln-cre mice revealed robust acceleration of atherosclerosis whose magnitude was indistinguishable from that of age-matched Apoe−/−Ltbr−/− mice (Figure 7A) and this acceleration was greater in the abdominal aorta when compared to other parts of the arterial tree (Figure 7B).