BCR and chronic myelogenous leukemia, BCR-ABL1 positive: Based on reports of over-expression of EphA2 in human leukemia and our own analysis of clinical samples, we examined expression of EphA2 gene in two models of leukemia, the MLL-AF9 model of acute myeloid leukemia and the BCR-ABL model of chronic myeloid leukemia [29].