Even within Tregs, the role of specific types, i.e., IL-10 secreting Tregs (that are more common in the lungs) and TGF-β secreting Tregs (more in the gut, but shown to play a role in asthma regulation) need to be studied in greater detail to establish a pathway and hence come up with viable solutions for treatment of asthma. This evidence concerns the gene TGFB1 and asthma.