To confirm that selected miRs are able to inhibit uPAR and CXCR4 expression in AML cell lines, we evaluated their effect on uPAR/CXCR4 expression in the pro-monocytic THP-1 cells, which showed lower miR levels and higher uPAR/CXCR4 expression as compared to KG1 cells (Fig.3). The gene discussed is PLAUR; the disease is acute myeloid leukemia.