Additionally, curated information from the Catalogue of Somatic Mutations in Cancer (COSMIC) database revealed that mutations in the coding-region of SF3A1 were associated with several cancers, including esophageal adenocarcinoma, myxoid liposarcomas, synovial sarcomas, osteosarcomas, endometrial tumors, lung cancer, breast cancer, ovarian carcinoma, gastric cancer and glioblastoma. The gene discussed is SF3A1; the disease is breast cancer.