SF3A1 and cancer: Additionally, curated information from the Catalogue of Somatic Mutations in Cancer (COSMIC) database revealed that mutations in the coding-region of SF3A1 were associated with several cancers, including esophageal adenocarcinoma, myxoid liposarcomas, synovial sarcomas, osteosarcomas, endometrial tumors, lung cancer, breast cancer, ovarian carcinoma, gastric cancer and glioblastoma.