CXCR2 and neoplasm: Elimination of Gr-1+ leukocytes in athymic nude mice slowed the growth of a variant of a UV light–induced tumour [46], and DMBA/TPA-treated mice that lack CXCR2, the chemokine receptor for KC and MIP-2, showed a reduced neutrophil chemotaxis and resistance to skin tumourigenesis [47].