Similarly, we observed that serum HMGB1 levels were related with the levels of anti-dsDNA antibody (r = 0.7278, P = 0.0004, Figure 1(h)) and urine protein (r = 0.6652, P = 0.0019, Figure 1(i)) in ALD-DNA-induced murine model of SLE. Here, HMGB1 is linked to systemic lupus erythematosus.