For example, the expressions of CSE and CBS proteins in hearts were decreased by about 80% and 60%, respectively, after myocardial infarction [62], and the plasma H2S concentration was significantly decreased to 53.3 ± 2.7 μmol/L compared to the controls (65.1 ± 1.5 μmol/L), while the percentage of fibrosis size to total area of left ventricle in rats of myocardial infarction was more than twofold higher than that in controls (25.7 ± 1.2% versus 12.5 ± 0.5%; P < 0.01) [61]. This evidence concerns the gene CBS and myocardial infarction.