Epidermal growth factor receptor (EGFR)-linked survival pathways including extracellular signal-regulated kinases (ERKs) 1/2 [75–77], phosphoinositol-3-kinase (PI3K)/protein kinase B (AKT) signaling pathways [78], and the downstream mTOR are involved in cell growth and survival, and they are often found to be activated in mesothelioma [79]. The gene discussed is AKT1; the disease is mesothelioma.