Using two different primer pairs that either bound within the RET kinase domain or flanked the CCDC6-RET fusion site, we confirmed by quantitative PCR that Lc2/ad cancer cells, but not several KRAS wildtype and mutant CRC cells, harbored the CCDC6-RET fusion kinase (Figure 2A) [13]. This evidence concerns the gene KRAS and colorectal carcinoma.