As shown in Table 1, REG4 protein expression was detectable in normal ovarian tissue (23.1 %, 6/26), benign ovarian tumors (70 %, 7/10), borderline ovarian tumors (81.8 %, 18/22), primary cancer (50.6 %, 119/235) and metastatic carcinoma in the omentum (61.4 %, 27/44). The gene discussed is REG4; the disease is cancer.