However, CD47 is broadly expressed on hematopoietic cells and other normal tissues 17, and the enhanced expression of CD47 has been reported on tumor cells in a variety of hematopoietic malignancies and solid tumors, such as leukemia 6, bladder cancer 18, astrocytoma 19, prostate cancer 20, and leiomyosarcoma 21. This evidence concerns the gene CD47 and Familial prostate cancer.