For glioblastoma-BTICs, the levels of CCR4, CCR10, XCR1, CXCR1, CXCR4, TEK, CD44 and IFNR were increased, but those of CX3CR1, IL1R, IL6R, IL8R, IGF1R and PDGFR-bb were decreased (p<0.05, Fig 4C). The gene discussed is IL1R1; the disease is glioblastoma.