IGF1 and myopia: [27] Furthermore, a study in Caucasians which reported that rs6214 in IGF-1 exhibited a significant association with high myopia was not included in this meta-analysis, because it was a family-based design and lacked available data; [25] a cohort study in polish families not finding any significant associations between IGF-1 SNPs (including rs6214) and high myopia, was also excluded in this meta-analysis for its family-based design and only including information about IGF-1 rs6214.