However, the image presented by Klover et al. as evidence for their statement that “A complete lack of STAT1 expression is observed in Stat1fl/fl NIC mice” was illustrated in Fig 4 in “Non–tumor-containing epithelium from approximately 1 year-old tumor-bearing mice is shown.” The epithelium illustrated was identified as hyperplastic and perhaps neoplastic by our experienced pathologists. Here, STAT1 is linked to neoplasm.