General linear model analysis showed that rs28362491 was associated with IL-6 levels by analyses of a dominant model (P<0.001) and a recessive model (P<0.001), and the difference remained significant after adjustment for age, sex, smoking, BMI, hypertension, diabetes, glucose, TG, TC, HDL, and LDL (Table 7). The gene discussed is IL6; the disease is diabetes mellitus.