Serous ovarian carcinomas with late stages III and IV displayed the highest level of CA125 in plasma (21S-High-IIIC—2005.7U/ml, 22S-High-IV—6547.7U/ml) whereas the level of CA125 in plasma from mucinous ovarian carcinomas at stages III and IV were much lower (9M-LowIIIC-141.6U/ml, 10M-Low-IV-195.57U/ml). The gene discussed is MUC16; the disease is ovarian mucinous adenocarcinoma.