All 20 LS-associated ovarian carcinomas did not show mutations on TP53, KRAS (exon 2), or BRAF (V600E), while, in sporadic ovarian carcinomas, TP53 was often abnormal (overexpressed or completely missing) and KRAS (exon 2) mutations occurred with a frequency of 8%. Here, TP53 is linked to ovarian carcinoma.