BCL2 and cancer: A corroboration of whether curcumin has a similar impact on miR-21, 143, and let-7 in female cancers may be important, as miR-21 overexpression is associated with invasive CC, miR-143 overexpression was linked to Bcl-2 inhibition in HeLa cells and restoration of let-7b in OC cells dramatically reduced tumor cell growth (98, 167, 168).