Since curcumin is able to inhibit the formation of reactive oxygen species (ROS) and the c-Jun NH2-terminal kinase (JNK) pathway, the group suggested that patients receiving camptothecin, mechlorethamine, doxorubicin, or other chemotherapeutics, which exert their anti-tumor effects by generating ROS and activating JNK, ought to take precautions when consuming curcumin (170). The gene discussed is MAPK8; the disease is neoplasm.