BDNF and Behcet disease: The behavioral alterations observed in BD patients are linked to central mechanisms, such as the following [7, 31]: (i) alterations in monoamine levels, for example, the dopamine dysregulation syndrome; (ii) mitochondrial dysregulation; (iii) alterations in calcium homeostasis; (iv) neuroinflammation; (v) oxidative imbalance; and (vi) dysregulation in neurotrophin's levels.