Multiple studies have reported increased levels of sIL-2R, sIL-6R, TNF-α, sTNFR1, IL-1, ILl-12, and TGF-b in BD, while mixed results have been reported for other inflammatory factors, including IL-4, IL-2, IL-8, and IFN-γ [25, 27, 30, 32, 38, 40, 42, 44–47]. This evidence concerns the gene IFNG and Behcet disease.