Mutations of CSNK1A1 were identified in approximately 7% of MDS del(5q) cases analyzed.15 A CSNK1A1 mutation was reported in a del(5q) MDS patient in a previous study.27 Interestingly, Schneider et al showed that expression of mutant CSNK1A1 resulted in β-catenin activation and HSC cell cycle progression. Here, CSNK1A1 is linked to myelodysplastic syndrome.