CXCL10 and arthritic joint disease: Mice deficient in NKT cells (CD1d−/−) exhibited enhanced arthritis severity, while α-GalCer treatment of C. trachomatis-infected wild-type mice increased the accumulation of NKT cells within synovial tissues, reduced bacterial load, suppressed expression of inflammatory chemokines [macrophage inflammatory protein-2 (MIP-2) and IP-10/CXCL10], and decreased infiltration of inflammatory cells into the inflamed joint.