Further, sessile KCs are radiation-resistant (Klein et al., 2007) and kinetic studies revealed that 85% of the recipient KCs remain in the liver 2 months after standard bone marrow transfer (BMT); even after 1 year, less than half of the original KC population is replaced (Kennedy and Abkowitz, 1997; Seki et al., 2009; Inokuchi et al., 2011). The gene discussed is TBCE; the disease is keratoconus.