Polymorphisms in genes of the inflammatory and thrombotic pathways, as well as the plasma levels of the resulting gene products including, CD40 ligand and MCP-1, may be of particular interest to future studies, as these processes have been implicated in the development of nerve damage in several diabetic neuropathies and have also been linked to other diabetic complications including ischemic stroke (289–291). Here, CD40LG is linked to diabetic neuropathy.