NR3C1 and post-traumatic stress disorder: The association in the present paper between corticolimbic dysregulation and NR3C1 methylation supports the hypothesis that a maternal endophenotype which carries a low mean percentage of NR3C1 methylation is likely to be associated with parenting stress and that parenting stress, coupled with maternal IPV-PTSD likely adversely impacts the quality of maternal behavior (i.e., maternal sensitivity and responsiveness to child bids for joint attention; Schechter et al., 2010).