To date, more than 100 GJB2 mutations have been identified to be associated with deafness [connexins and deafness Web site: http://davinci.crg.es/deafness/index.php, and also see Mani et al. (2009), Castillo and Castillo (2011), and Chan and Chang (2014)]. The gene discussed is GJB2; the disease is deafness.